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Of the infants in the study there were
2023-08-26
Of the 580 infants in the study, there were 106 twin deliveries and 10 triplet deliveries. There was no difference in prenatal antibiotic exposure between multiple and singleton births. Nevertheless, analysis of maternal antibiotic use was based on the 309 individual mothers who were provided AS-252
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Angiogenesis is a process of formation of new vessels from
2023-08-26
Angiogenesis is a process of formation of new vessels from arterial vascularization created by endothelial cells. It is essential for the continuous growth of the tumor because it supplies the tumor with nutrients and oxygen, and eliminates cellular waste, which can be toxic to cancer cells [8]. Inf
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br Acknowledgements br Introduction The
2023-08-26
Acknowledgements Introduction The angiogenic ocular conditions represent the most common cause of blindness in developed countries [1]. It can affect all ages, for example, retinopathy of prematurity (ROP) in infants [2], [3], diabetic retinopathy (DR) [4] in working age adults and age-related
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Recent studies suggest that A caused synapse damage
2023-08-26
Recent studies suggest that Aβ caused synapse damage as a consequence of aberrant cell signalling. As synthetic Aβ42 monomers activate the phosphatidylinositol-3-kinase pathway (Giuffrida et al., 2009) and insulin signalling (Giuffrida et al., 2012) it is possible that Aβ monomers and Aβ oligomers a
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br Acetaldehyde One of the most common http www
2023-08-26
Acetaldehyde One of the most common environmental aldehydes is acetaldehyde (CH2CHO). Acetaldehyde, which is highly volatile, has been classified as a Group I human carcinogen by the International Agency for Research on Cancer [30]. Aldehydes can form DNA adducts, including ring-open forms of cro
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Streptomycetes are a group of filamentous Gram
2023-08-25
Streptomycetes are a group of filamentous Gram-positive, soil-inhabiting bacteria which have captured enormous screening interest because of their ability to produce and secrete a variety of neuropeptides and extracellular proteins [7]. Among the diverse antibiotics produced by Streptomycetes are t
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We have previously reported that interfering with actin asse
2023-08-25
We have previously reported that interfering with pilocarpine hcl assembly dynamics by knocking down cofilin-1 in hMSCs increased polymerized actin that promoted osteoblast cell differentiation through a mechanism of enhancing focal adhesion kinase (FAK), p38 and c-Jun N-terminal kinase (JNK) signa
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The bovine Ack is called Ack bAck
2023-08-25
The bovine Ack is called Ack2 (bAck2) and has been suggested to act as a clathrin-assembly protein regulated by the small GTPase Cdc42 [17]. bAck2 lacks some of the C-terminal parts when compared to hAck1 and mAck1. Both Ack1 and Ack2 have been demonstrated to interact with sorting nexin 9 (SNX9 or
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During years research efforts at Los Alamos National
2023-08-25
During 2002–2004years research efforts at Los Alamos National Laboratory (LANL) focused on constructing a quantum computer based on regular arrays build from neutral radical molecules possessing one single unpaired GM6001 spin. The idea was built on the ability to manipulate individual electron spin
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The results show that a tonic action of
2023-08-25
The results show that a tonic action of ACh on respiration is lacking. However, it is clear that muscarinic cholinergic mechanisms can modulate both eupneic breathing and the cough reflex. When these mechanisms are brought into action is obscure and only tentative proposals can be advanced. ACh in t
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CHK has been reported to
2023-08-25
CHK1 has been reported to be the kinase responsible for H3.3S31 phosphorylation in human ALT cancer VKGILS-NH2 . However, in our study, knockdown of CHK1 in HEK293F (Figs. S1c and S6) or HeLa S3 (data not shown) cells did not result in a significant decrease in H3.3S31ph, which is in agreement with
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For the TSH receptor signaling at the Golgi trans
2023-08-25
For the TSH receptor, signaling at the Golgi/trans-Golgi network appears required for both rapid effects of TSH − such as Dyphylline depolymerization, which is implicated in thyroglobulin reuptake and, thus, thyroid hormone release − and late ones, such as those on gene transcription. Continued sig
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br Interaction between ASK and TRX Thioredoxins are small kD
2023-08-25
Interaction between ASK1 and TRX Thioredoxins are small (∼12kDa) dithiol oxidoreductases ubiquitously expressed in species ranging from plants to archaea and mammals. They perform various biological functions, such as reducing protein disulfide bonds, supplying reducing equivalents to redox Loxap
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In the current study SA was assessed to confirm
2023-08-25
In the current study, SA was assessed to confirm the safety of CS addition to erythrocytes SA as well as SA elicits antioxidant action. It has been reported that, ROS induced desialylation by depletion of SA content from cell surfaces (Pawluczyk et al., 2014, Harisa, 2015). Therefore, significant de
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br Experimental EPR spectra of
2023-08-25
Experimental EPR spectra of probes 1a–f were recorded on a Bruker EMX-1572 operating at X-band (9.0–9.9 GHz), at 21 ± 1 °C. The EPR parameters were the same in all experiments: microwave power, 1 mW; modulation amplitude, 5 G; time constant, 10.24 ms; and conversion time, 40.96 ms. Reduced gluta
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