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br Introduction Mantel cell lymphoma MCL
2018-11-01
Introduction Mantel cell lymphoma (MCL) is a rare B-cell non-Hodgkin\'s lymphoma with a poor long-term prognosis. Skin involvement occurs in only 2–6% of all cases of MCL, but is seen in 17% of stage IV patients. It is important for the dermatologist to realize and master the primary clinic prese
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Tasquinimod Clinically exogenous ochronosis appears very
2018-11-01
Clinically, exogenous ochronosis appears very similar to melasma. Other differential diagnoses include bilateral nevus of Ota, Riehl melanosis, acquired bilateral nevus of Ota-like macules, postinflammatory hyperpigmentation, and drug-induced hyperpigmentation, such as minocycline and amiodarone. A
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Here we present the first case in Asia
2018-11-01
Here, we present the first case in Asia of sarcoidosis with bilateral leg lymphedema as the initial presentation. Notably, cutaneous manifestation is common in sarcoidosis. This case reminds us to consider sarcoidosis in the differential diagnosis of leg lymphedema, thereby prompting early diagnosis
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br Correlation Hardness and ultrasonic wave
2018-11-01
Correlation Hardness and ultrasonic wave velocity measurements are performed before and after each annealing stage. Their variation in initial condition are investigated in terms of annealing temperature, and then the variations of hardness and ultrasonic wave velocity are correlated for each ste
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order DYKDDDDK La noci n de control
2018-11-01
La noción de control total es un gancho bastante frágil en el cual colgar el concepto de esclavitud. De hecho, si se usa esta definición, muchos de los antiguos esclavos no contarían como nuevos esclavos; por ejemplo, no todos los de las sociedades esclavistas en Estados Unidos y el Caribe eran cont
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In the formalin test ketorolac at
2018-10-31
In the formalin test, ketorolac at a dose levels of 15 mg/kg, 30 mg/kg and 60 mg/kg exerted better analgesic effect demonstrated at the late phase of the nociceptive response which may be due to its peripheral anti-inflammatory effect. Following irradiation, treatment with ketorolac exerted a more p
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Real exchange rate is positively significant only in
2018-10-31
Real exchange rate is positively significant only in case of China and it has no effect on FPI volatility in case of remaining three countries. China is not trading in primary goods so fluctuation in exchange rate does not exist, so RER has significant positive effect on portfolio investment volatil
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The actual incidence leading to
2018-10-31
The actual incidence leading to FES in sickle cell disease patients is difficult to be determined due to the lack of diagnostic tests. Currently, there are two criteria proposed for the diagnosis of FES. Gurd’s criteria require at least one major feature (respiratory insufficiency; cerebral involvem
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br Materials and methods br Statistical analyses Results
2018-10-31
Materials and methods Statistical analyses Results were expressed as mean±SEM (standard error of mean). Multiple group comparisons were performed by one-way analyses of variance (ANOVA) followed by the Bonferroni procedure for comparison of means. Comparisons between two groups were performed
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egfr pathway Like many of the established animal based ex
2018-10-31
Like many of the established animal based ex vivo cardiac safety pharmacology models (Langendorf, Purkinje fiber, ventricular wedge) the present assay is based on measuring the net cellular electrical activity (monophasic egfr pathway or field potential in case of the MEA) instead of a single isola
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neuraminidase inhibitors To help define the chicken ES cells
2018-10-31
To help define the chicken ES cells and PGC better, it would be advantageous to study the expression profiles of various genes related to pluripotency and to the germ cell identity, as has been done in mammalian cells (see Pashai et al., 2012). Here we report a comparative microarray analysis using
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br Nonhuman primate models for transplantation therapy motor
2018-10-31
Nonhuman primate models for transplantation therapy: motor and non-motor manifestations of the MPTP lesion Methods that have been used to induce a parkinsonian state in NHPs include 1-methyl-4-phenyl-1,2,3,6 tetrahydropyridine (MPTP) administration (Emborg, 2007), 6-hydroxydopamine administration
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The Sonic Hedgehog SHH pathway is active in the
2018-10-31
The Sonic Hedgehog (SHH) pathway is active in the adult SEZ, where it has been proposed to regulate cell proliferation (Ruat et al., 2012; Ahn and Joyner, 2005; Machold et al., 2003) and to modulate the migration of neuroblasts exiting the niche (Angot et al., 2008). The mosaic inactivation of the S
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Constitutive expression of Puro TK
2018-10-31
Constitutive expression of Puro/TK from the ubiquitously active mPGK promoter might hinder therapeutic applications of this approach. Indeed, these highly immunogenic prokaryotic/viral proteins can be presented on the cell surface of the gene-corrected purchase ICG-001 by the major histocompatibilit
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Comparative analysis of transgenic hPAX GFP
2018-10-31
Comparative analysis of transgenic hPAX6GFP expression revealed similarities between the retinal organoid system and the mouse retina in vivo. Our analyses indicated a similar sequence of hPAX6GFP+ retinal cell types in mice in vivo, and in mESC- and hESC-derived retinal organoids: progenitors and r
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