• Antioxidative enzymes such as SOD and

  2025-01-20

  

  Antioxidative enzymes such as SOD and CAT play prominent roles in protecting against oxidative stress and extending food freshness due to their ability in scavenging active oxygen species for maintaining cell membrane integrity. Evidence shows that activities of SOD and CAT are positively affected b

• Mechanistically it was soon realized that in

  2025-01-20

  

  Mechanistically, it was soon realized that in undead cells, Dronc promotes the activation of Jun-N-terminal kinase (JNK) signaling as the major inducer of AiP [25], [28] (Fig. 2B,C). However, it has been unknown for a long time how active Dronc promotes JNK signaling. Recently, it was reported that

• Interestingly as observed with Treg cells adenosine can regu

  2025-01-20

  

  Interestingly, as observed with Treg cells, adenosine can regulate the function of Breg cells, a subset of immunosuppressive cells that support immunological tolerance [115]. In particular, Bregs were able to regulate both their own function and T cell activity via an adenosine signaling originating

• br A Rs which were cloned and

  2025-01-20

  

  A3Rs, which were cloned and then pharmacologically identified in the early 1990s, are expressed in multiple organs and peripheral tissues including prothrombinase complex inhibitor involved in inflammatory responses (Gessi et al., 2008, Borea et al., 2014). While low levels are expressed in the C

• Tension within the network could be explained by two

  2025-01-20

  

  Tension within the network could be explained by two potential mechanisms: the more classical contractility that is dependent on motor proteins that are pulling TMN 355 receptor filaments towards each other [10]; or contractility that is caused by disassembly of a crosslinked network of actin filam

• Along with the improvement of the cadmium

  2025-01-18

  

  Along with the improvement of the cadmium transport from roots to aerial tissues, as is required for phytoremediation, over-expression of PtoHMA5 also led to the excessive accumulation of cadmium in leaves that was harmful to plant growth and physiological performance. Thus, detoxification of the he

• Why do glutamate and glycine bind

  2025-01-18

  

  Why do glutamate and glycine bind to the A-54556A activity in such different ways? Given the overall structural similarity between the GluN2A and GluN1 LBDs, one might conclude that the LBDs also bind ligands via similar processes. NMDA receptors with engineered disulfide linkages that lock the Glu

• In order to determine whether the faster Rh induced

  2025-01-18

  

  In order to determine whether the faster Rh2-induced apoptosis is specific of cholesterol depletion, we determined the cytotoxic effect of Rh2 in Cucurbitacin B depleted or not in sphingomyelin, another abundant plasma membrane lipid exhibiting enrichment in lipid rafts. We showed that, in contrast

• To circumvent these issues multiple approaches

  2025-01-18

  

  To circumvent these issues, multiple approaches have been developed that target small fractions of the genome, thus reducing the sequencing burden (Dostie et al., 2006; Fullwood et al., 2009; Mumbach et al., 2016). Application of one such approach, chromosome conformation capture carbon copy (5C), w

• br Results br Discussion Using primarily an

  2025-01-18

  

  Results Discussion Using primarily an electrophysiological analysis of dysbindin-deficient hippocampal neurons in cultures and slices, we have uncovered a previously unreported role for dysbindin in enhancing CA3–CA1 AMPAR-mediated transmission. An earlier study, however, has reported a reduct

• br Materials and methods br Results

  2025-01-17

  

  Materials and methods Results Discussion Wound healing of the human cornea is a complex process that requires cell migration and proliferation. Corneal wound healing is characterized by major changes in the composition of the ECM such as a massive transitory secretion of fibronectin combine

• 5104 mg Our previous study revealed expression of AhR

  2025-01-17

  

  Our previous study revealed expression of AhR in human parotid gland in cytoplasm of striated duct 5104 mg (Drozdzik, Kowalczyk, Urasińska, & Kurzawski, 2013). In a further study we observed regulation of AhR expression and function by its specific inducer, i.e. 2,3,7,8-tetrachlorodibenzo-p-dioxin

• The study by Lo http

  2025-01-17

  

  The study by Lowry et al. (2001) pointed toward functionally uncharacterized DA- and 5-HT-accumulating neurons within the DMH as a potential target for rapid nongenomic effects of CORT. Similar DA- and 5-HT-accumulating systems are distributed throughout the central and peripheral nervous systems, s

• Neural progenitor cells NPCs are self renewing multipotent c

  2025-01-17

  

  Neural progenitor cells (NPCs) are self-renewing, multipotent cells that are capable of differentiating into neurons, astrocytes and oligodendrocytes. NPCs are activated in response to a variety of pathological states in neurodegenerative diseases such as Parkinson’s disease and multiple sclerosis,

• MicroRNA miRNA is an abundant group of

  2025-01-17

  

  MicroRNA (miRNA) is an abundant group of small (22-nucleotide) noncoding RNA molecules that directly binds with 3′ untranslated region (UTR) of target messenger RNAs (mRNAs) to regulate gene expression, playing an important role in variety of biological processes including cell proliferation, apopto

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