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br Introduction The offspring of rodents emit vocalizations
2020-08-13
Introduction The offspring of rodents emit vocalizations when isolated from their dam. The majority of vocalizations by rat pups are in the ultrasonic band frequency of 30–50 kHz (Insel et al., 1986). Maternal separation-induced ultrasonic vocalizations are believed to represent distress signals
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Mutation in BRCT II domain
2020-08-12
Mutation in BRCT-II domain (W893R) either in the full-length context or the C-terminal context greatly reduced the expression of LIG4 (Fig. 2B, Fig. 3B), suggesting the importance of BRCT-II domain in the maintenance of LIG4. In this regard, it might be noted that LIG4 protein was undetectable in Li
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The CysLT receptor antagonist BayCysLT RA significantly supp
2020-08-12
The CysLT2 receptor antagonist BayCysLT2RA significantly suppressed multiple antigen challenge-induced infiltration of eosinophils and mononuclear 78416 into the lung, indicating that CysLT2 receptor activation is involved in leukocyte migration. In contrast to the present finding, Barret et al. [2
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br Conclusion In vivo pharmacokinetic studies showed that
2020-08-12
Conclusion In vivo pharmacokinetic studies showed that dasatinib monohydrate pretreatment significantly decreased the blood level of CsA in rats, which was most probably due to the induction of CYP3A2 isoenzymes. The nilotinib pre-treatment had no significant effects on cyclosporine pharmacokinet
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The oxidation of the lipid
2020-08-12
The oxidation of the lipid fraction of meat is an extremely complex process because of the high sensitivity of oxidation products to decomposition, their reactions with other components, the complex effect of catalysts and the presence of antioxidants. These changes are the main cause of limited sh
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In the present study we investigated the effect of
2020-08-12
In the present study we investigated the effect of morphine withdrawal on G-protein coupling to opioid and ET receptors in neonatal rats. Morphine-induced G-protein activation was significantly higher in neonatal rats undergoing morphine withdrawal; suggesting enhanced coupling of the receptors to G
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br Conclusion The results of the current
2020-08-11
Conclusion The results of the current study show that boldness is associated with higher gene expression of drd2a, drd2b and oprd1b in zebrafish males. The results are correlational and additional experiments are needed to clarify the causal role of these receptors in zebrafish behavior. Confl
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Because stimulation and blockade of dopamine D receptor all
2020-08-11
Because stimulation and blockade of dopamine D2 receptor all cause a similar disruption of maternal behavior, one critical question is whether they do so through the same or different behavioral mechanisms. One idea is that stimulation or blockade of D2 receptors similarly suppresses maternal motiva
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br Results br Discussion In this study we have determined
2020-08-11
Results Discussion In this study, we have determined the pathway by which the 3ʹ end of the nascent leading strand is connected with CMGE after priming, revealing that Pol δ likely plays a crucial role in establishing all continuously synthesized leading strands at eukaryotic replication origi
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buy penicillin Reports on the participation of
2020-08-11
Reports on the participation of NDH2 along with other respiratory complexes in the formation of a large supercomplex (Grandier-Vazeille et al. 2001) or even a respirosome-like structure in S. cerevisiae mitochondria (Matus-Ortega et al. 2015) are very intriguing. Similarly, in Y. lypolytica mitochon
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br Results and discussion A systematic search for
2020-08-11
Results and discussion A systematic search for genes encoding H+-PPases was carried out by PCR using genomic DNA from a wide range of protozoa as templates and degenerate oligonucleotides, designed from amino Z-DEVD-FMK domains conserved in H+-PPases of higher plants and the proteobacterium R. r
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CDK S phosphorylation status influences the differential
2020-08-11
CDK5-S47 phosphorylation status influences the differential cellular proliferation versus migration response: Previous work from our laboratory has shown CDK5 to be a critical determinant of the cellular proliferation-migration dichotomy whereby CDK5 activation downstream of stimulated epidermal gro
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br Bipartite graph br Algorithm
2020-08-11
Bipartite graph Algorithm for CFC Error detection rate and overhead evaluation Test results and discussion For verifying the proof in GSK2578215A from the perspective of practice, this section brings tests and analysis based on the onboard computer (OBC) of the in-service ZDPS-1A pico-s
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br Conclusion br Conflicts of interest
2020-08-11
Conclusion Conflicts of interest Acknowledgements This study was financially supported by The Science and Engineering Research Board (SERB), Department of Science & Technology (DST), Government of India under the Fast Track Scheme for Young Scientist to Dr. V. Dhananjayan (No: SB/FT/LS-140/
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To further verify the effect of BBR
2020-08-11
To further verify the effect of BBR on ACAT2 protein expression, we have conducted an in vitro permeability assay using Caco-2 monolayer. This assay has long been used to predict the in vivo Cy3 maleimide (non-sulfonated) synthesis and bioavailability of a compound. It was observed that the amount
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